LifeForge Disposable Mixing Solution

the above two kinds of mixing bags adopt magnetic levitation technology, which completely avoids the generation of particles caused by the friction of bearings or impellers. Depending on your specific application and environment, including sterile docking, from cell culture to final filling, you can configure the appropriate filters, connectors and tubing. Our proven, scalable, direct-to-use system and process technologies reduce the risk of contamination, improve economics and process flexibility, and achieve repeatable results.

LifeForge disposable mixer

LifeForge disposable mixer series has the best mixing performance and process turnover rate. Each disposable mixing bag includes a magnetic suspension impeller to improve the consistency and efficiency of mixing. Unlike traditional stainless steel mixers, disposable mixers reduce downtime due to CIP, SIP, and cleaning verification. The Ruitoto disposable mixer also has the flexibility to operate and can be up and running in five minutes. Stirring speeds of up to 1000 RPM * meet the requirements of a variety of mixing production. * Depends on agitator size.

Reliable, tough PuRobust film and PureSupply + film

mixing bag can be made of PuRobust or PureSupply + film, while the dry powder dosing bag is made of PureSupply + film. LifeForge disposable process container film series is a high purity, medical grade multi-layer co-extruded film, with high strength, high ductility, excellent air tightness and biocompatibility. The liquid contact layer of the film is made of ultra low density polyethylene (ULDPE). The air barrier layers of the films were all made of polyethylene-vinyl alcohol copolymer (EVOH). The outer layer of the PuRobust film is made of LDPE, and the outer layer of the PureSupply + film is made of nylon.

reduce the risk of contamination	Easy to install and use
reduce downtime due to cleaning validation	closed sterile sampling system for representative sample collection
validation, quality and regulatory support	can efficiently mix the most challenging buffers, media and pharmaceutical ingredients *(high-performance mixing bag is more obvious)
single-use technology to increase the capacity of multi-species parallel facilities	working volumes, from a minimum working volume of approximately 10% to a maximum working volume of 120% *; is suitable for flexible and variable processes. (* Depending on specific mixing system type and specifications)

Stir evenly

mounted bottom-mounted deflectable levitation magnetic impeller provides uniform agitation performance.

No stir bar	Bearingless
No support rod	No mechanical contact

Faster process turnaround

LifeForge mixing systems are ideal for multi-species facilities with high production requirements. The installation of this disposable mixing bag is very simple and can be completed within 5 minutes. After installation, the operator only needs to turn on the agitator to start mixing, which significantly improves the turnover and productivity of the process.

Safe and sterile, sampling directly from the Ruitto mixing bag

All LifeForge mixing bags can be equipped with one or several needle-free sampling bags (depending on the user's process requirements). The closed design allows the user to take samples directly from the mixing bag without the risk of cross-contamination. After the sampling is completed, the separation of the sampling bag from the mixing bag is achieved by means of a sterile pinch-off tool (a sterile break-off ring on the sampling tube is pinched off to form two closed sterile ends)

Ensure optimum mixing performance and reliability

Ensuring optimal mixing performance is critical throughout the user's process development, process scale-up and production. Our expert team provides users with a full range of services to ensure that the user's disposable mixing system has a continuous and trustworthy mixing performance

Dry powder feeding

LifeForge Dry Powder Feeding Bag

unique asymmetric dry powder feeding bag for better powder flow	4 inch port to prevent arching effect
optional volume: 5, 10, 15, 25 L	Optional flushing tank

LifeForge dry powder feeding bag can choose flushing function. The flushing function safely and effectively flushes residual powder from the dry powder dosing bag directly into the mixer. This feature also allows the user to safely handle the dry powder dosing bag.

in a wide range of applications in the biopharmaceutical field (e. g. preparation, storage and transportation of formulations, sterile solutions or buffers), the Ruitetop standard components provide a convenient disposable solution. The individual components of these standard components are free of animal origin and are pre-sterilized by gamma radiation before leaving the factory and ready to be used directly in your existing production process.

Specifications

conventional mixing bag	10L, 50L, 100L, 200L, 500L, 1000L
high performance mixing bag	100L, 200L, 500L, 1000L and 2000L
structure material
mixing bag body	PuRobust membrane
Port connector	LDPE
Luer connector	PP
CPC Fitting	PC
Line	Silicone
water stop clamp	POM
impeller	PP, connotation magnet
4 "feeding port	HDPE
TC gasket	Silicone
TC Clamp	Nylon
TC Blind	PP
impeller cup	HDPE

dry powder feeding bag
structure material
Dry powder feeding port	PE
Clamp	Nylon
blind plate	PP
Feeding bag body	PuRobust membrane
volume (L)	5, 10, 15, 25
weight (kg)	5, 10, 15, 25
Feeding port	4 "TC chuck
Flushing port	1/4"

PM series and NM series disposable mixing system

Hardware specifications cover 10L-2000L, optional jacket, weighing, temperature, pH, conductivity, pressure, TCU configuration

Features and Advantages

round tank design:

Engineering shape design, to achieve efficient mixing at the same time, avoid the existence of mixing dead.

Eccentric inclined blade:

At the bottom of the mixing motor and paddle for eccentric oblique placement, can provide both radial and axial mixing.wide door design:

The bottom of the tank and mixing bag is conical design, and the liquid outlet is located at the lowest point to ensure that the product can be discharged under gravity.

to avoid the loss of valuable products.

10% minimum working volume:

Mixing bags with different volumes have different blade sizes. With the design of conical bottom, the minimum working volume can be as low as about 10% *, avoiding foam during stirring at low liquid level and protecting product activity.

(* depends on specific mixing system type and specifications)

brand hardware:

The key components of the mixing system are Panosonic, Nord, Levitronix, Mettler Toledo,Labom and other brands, with reliable quality and accurate measurement results to ensure the reliability of system operation.

Easy to operate:

Optional touch screen, user can select manual and automatic operation mode in HMI.

Reliable data:

The HMI data recording function generates the original data that cannot be modified, and finally exports it in the form of a report to ensure the true validity of the production record.

Model and technical parameters

Note: Size and weight vary slightly depending on configuration. Stirring is the default function, weight/temperature/pH/conductivity/pressure and jacket are all optional configurations, and the sensor range can be customized.

Stirring motor: protection grade IP55

Pressure: protection grade IP65

Weighing system: protection grade IP68

The control cabinet: 304 stainless steel, protection grade IP54

Temperature: protection grade IP67

Tank body: 304 stainless steel, Ra≤ 0.8

pH/conductivity: protection class IP68